Discover how Ginsenoside Rp1 enhances anti-cancer effects of Actinomycin D by targeting the AKT-SIRT1 pathway to overcome drug resistance in cancer treatment.
Discover how SMR peptide derived from HIV targets mortalin to fight cancer through multiple mechanisms including disrupting extracellular vesicles and restoring immune recognition.
Explore how cell cycle checkpoints serve as the body's defense against cancer and how modern medicine is weaponizing these mechanisms to develop targeted anticancer therapies.
Discover how the sequence of administering paclitaxel and cisplatin dramatically impacts cancer treatment efficacy and safety in this scientific exploration.
Discover how DPQZ, a novel antitubulin agent, induces apoptosis in oral cancer cells through Ras/Raf inhibition and MAPK activation.
Explore BR101801, a novel triple-inhibitor therapy targeting PI3Kγ, PI3Kδ, and DNA-PK for advanced hematologic malignancies. Learn about preclinical insights and clinical trial results.
Explore how CK2 inhibitors like BMS-595 are reshaping cancer therapy by targeting tumor addiction pathways and modulating the immune microenvironment.
Discover how combining FLT-3 inhibitors with HSP90 blockers creates a synergistic therapy that effectively targets acute myelogenous leukemia with mutant FLT-3.
Explore how NVP-BEZ235 and NVP-BGT226 dual inhibitors enhance tumor radiosensitivity by targeting the PI3K/Akt/mTOR pathway in cancer treatment.
Discover how pH-sensitive gold nanorods with transferrin targeting are revolutionizing lung cancer therapy by delivering doxorubicin precisely to cancer cells while minimizing side effects.