Discover how targeting DNA Damage Response and anti-apoptosis genes offers new hope for treating Acute Myeloid Leukaemia in elderly patients through synergistic lethality.
Discover how epigenetic inactivation of miR-9 in chronic lymphocytic leukemia leads to constitutive activation of the NFκB pathway, driving cancer progression.
Exploring RIOK2 as an emerging therapeutic target for acute myeloid leukemia and other cancers through ribosome biogenesis inhibition.
Discover how TP73 isoforms predict survival and treatment resistance in Acute Promyelocytic Leukemia, offering new hope for personalized cancer therapies.
Discover how arsenic trioxide transformed from a deadly poison to a life-saving cancer therapy, with multiple mechanisms against various cancers.
Discover how realgar (As₄S₄), a traditional Chinese medicine, fights acute promyelocytic leukemia through the Bcl-2/Bax/Cyt-C/AIF signaling pathway.
Discover how trichosanthin from Traditional Chinese Medicine selectively targets leukemia cells through programmed cell death pathways.