Discover how TRAIL-R1 regulates TGFβ signaling through microRNA-370-3p in pancreatic cancer cells, revealing new therapeutic targets.
Discover how Cysteine 288 in NPM1c+ leukemia creates a redox-sensitive vulnerability that can be targeted with bortezomib therapy.
Exploring how m6A methylation orchestrates the destructive inflammation in rheumatoid arthritis through epigenetic regulation of synovial cells.
Explore how all-trans retinoic acid (ATRA) combats alcohol-induced endoplasmic reticulum stress and liver damage through cutting-edge research findings.
Discover how the SOX17-FUBP1 genomic interaction drives pulmonary arterial hypertension and the promising therapeutic approaches targeting this pathway.
Discover how Vitamin C activates IGFBP7 through the HIF-1α/VEGF pathway to potentially revolutionize chronic atrophic gastritis treatment.
Exploring how defective IL-4/Stat6 signaling and overexpressed suppressors SOCS-3, SOCS-7, and CISH contribute to colon cancer progression.
Breakthrough advances in radiation therapy for head and neck cancers from ASCO and ESMO 2022, focusing on precision, immunotherapy, and molecular targets.
Discover how GPx1 deficiency in macrophages leads to ferroptosis, exacerbating inflammation in Crohn's disease. Explore groundbreaking research and potential therapies.
Exploring how photobiomodulation can suppress oral squamous cell carcinoma through precise light wavelengths.