Research Articles
A Natural Molecule's Sneak Attack: How a Licorice Extract Fights Skin Cancer
Discover how Licochalcone A from licorice root activates autophagy to fight melanoma through the miR-142-3p/Rheb/mTOR pathway.
CRID3: The Molecular Key to Unlocking Spinal Cord Injury Recovery
Discover how CRID3, an experimental compound targeting inflammasomes, shows promise in treating spinal cord injury by modifying the immune response and promoting recovery.
How a Diabetes Drug Could Revolutionize Leukemia Treatment: The AMPK-RUNX1-STAT3 Connection
Discover how metformin-induced AMPK phosphorylation of RUNX1 inhibits STAT3 and overcomes imatinib resistance in chronic myelogenous leukemia (CML).
Frozen in Time: The Cellular Battle for Survival in a Revolutionary Cancer Therapy
Explore how cryopreservation affects mononuclear cell apoptosis in Extracorporeal Photopheresis (ECP) cancer therapy and the scientific breakthroughs in cellular preservation.
The Caffeine Paradox: How Your Morning Coffee Fights Skin Cancer
Discover how caffeine protects your skin from UV damage by inhibiting the ATR-Chk1 pathway in skin cells, potentially reducing skin cancer risk.
Nature's Hidden Weapon: How Nitidine Chloride Fights Melanoma
Discover how nitidine chloride, a natural plant compound, triggers cellular self-destruction in melanoma through AMPK-mTOR signaling pathway.
CHK1 Protein: Vulvar Cancer's Achilles' Heel?
Exploring CHK1 protein as a potential therapeutic target in vulvar squamous cell carcinoma treatment.
Unlocking Melanoma's Defense: How the Akt3 Protein Drives Resistance to Targeted Therapy
Explore how Akt3 protein enables melanoma cells to resist BRAF-targeted therapies and the scientific breakthroughs in overcoming this resistance mechanism.
The Red Wine Molecule's Hidden Power: Turning the Tide Against Breast Cancer
Discover how resveratrol, a compound in red wine, induces apoptosis in aggressive breast cancer cells through PI3K/Akt and p53 signaling pathways.
The Spice of Life: Can a Plant Molecule Save Our Muscles?
Exploring how quercetin, a natural antioxidant found in fruits and vegetables, protects muscle cells from dexamethasone-induced damage.