Research Articles
The Cellular Eraser: Engineering a Smarter Cancer Fighter
How scientists tested CG200745, a new HDAC inhibitor drug designed to wipe out cancer cells without wiping out the patient through DMPK and early toxicity studies.
The Secret Sentinel: A Tiny Protein from Telomerase RNA Shields Our Cells
Discover how hTERP, a small protein encoded within telomerase RNA, plays a crucial role in cellular protection against aging, stress, and disease.
The Bone Marrow Trap: How a "Welcome Mat" for Stem Cells Lures in Cancer
Discover how cancer cells hijack the bone marrow's natural stem cell homing system through Annexin 2 and CXCL12 interactions to establish deadly metastases.
The Cancer Conspiracy: Unraveling the Tangled Signals Inside a Tumor
Explore how HGF signaling and Ki-ras oncogene activation work together in colorectal cancer, uncovering the shared genetic targets that drive tumor growth and metastasis.
The Green Danger: How Unripe Papaya's Hidden Toxin Wreaks Havoc on Cellular Power Plants
Discover how unripe papaya's hidden toxin targets liver mitochondria, disrupting cellular energy production and triggering cell death pathways.
The Unhealing Wound: When Your Lungs Can't Stop Sounding the Alarm
Exploring how Danger-Associated Molecular Patterns drive the relentless scarring in Idiopathic Pulmonary Fibrosis and the promising research that could lead to new treatments.
Training the Body's Assassins: A New Front in the Fight Against Mesothelioma
How scientists are using a clever cellular trick to turn cancer against itself through apoptotic cell-pulsed dendritic cell vaccination.
The Gut Hormone Siblings: One Fights Diabetes, The Other Heals Your Gut
Explore how GLP-1 and GLP-2, two nearly identical gut hormones, send very different signals to regulate metabolism and gut health.
GSK-3 Inhibitors: The Diabetes Heart Dilemma
Exploring the delicate balance between therapeutic potential and cardiac safety in GSK-3 inhibitors for diabetes treatment.
The Guardian's Dilemma: How p53 Stops Cells from Self-Destructing
Discover how p53 protein prevents mitotic catastrophe in cells exposed to ionizing radiation, ensuring controlled cell death and genomic stability.