Explore how survivin protein enables breast cancer cells to resist chemotherapy through dual mechanisms of apoptosis inhibition and cell division regulation.
Discover how a copper-based molecule transformed into a powerful cancer-fighting compound through an unexpected lab accident and scientific innovation.
Discover how AKIP1 protein research challenges fundamental biological assumptions about protein localization and function in cellular processes.
Exploring how proteasome inhibitor MG132 affects NK/T cell lymphoma cells by disrupting their protein recycling system and inducing cell cycle arrest.
Discover how gemcitabine chemotherapy may inadvertently strengthen pancreatic cancer stem-like cells through the induction of lncRNA HOTAIR, creating treatment resistance.
Discover how SM-164, a Smac-mimetic compound, acts as a Trojan horse to make breast cancer cells more sensitive to radiation therapy by triggering apoptosis.
Discover how Olanzapine, a common mental health medication, protects PC12 cells from oxidative stress induced by hydrogen peroxide.
Discover how MHY218, a novel HDAC inhibitor, induces autophagic cell death in tamoxifen-resistant breast cancer cells, offering new hope for treatment-resistant patients.
Discover how CHD1L protein transforms from cellular guardian to cancer ally by activating the hnRNP A2/B1-nmMYLK axis in liver cancer development.
Discover how arsenic trioxide transformed from a deadly poison to a life-saving cancer therapy, with multiple mechanisms against various cancers.