Research Articles
The New Attack on Cancer: How Tumor-Targeting Taxanes are Revolutionizing Chemotherapy
Exploring groundbreaking advances in tumor-targeting taxane agents that are reshaping cancer therapy through precision drug delivery and next-generation compounds.
The Pregnancy Paradox: How a Short Estrogen Burst Prevents Breast Cancer
Discover how short-term estradiol treatment mimics pregnancy's protective effect against breast cancer through molecular reprogramming of mammary tissue.
How a Gum Infection Can Fuel Joint Destruction: The Silent Impact of Bacterial Lipids
Discover how lipids from Porphyromonas gingivalis bacteria in gum disease can trigger cartilage destruction by promoting programmed cell death in joint cells.
Alpha Particles and Cellular Self-Destruction: A New Frontier in Multiple Myeloma Treatment
Discover how alpha particles trigger autophagy in multiple myeloma cells, offering new hope for targeted cancer therapy and precision medicine approaches.
From Tragedy to Triumph: The Celgene Thalidomide Revolution
The remarkable story of how Celgene transformed thalidomide from a pharmaceutical pariah to a life-saving treatment for cancer and inflammatory diseases.
Breaking Bad: How an Arthritis Drug Could Help Fight a Rare Nerve Cancer
Discover how COX-2 inhibitors like etodolac trigger apoptosis in Malignant Peripheral Nerve Sheath Tumors by activating caspase pathways.
AF8c: How a Multi-Kinase Weapon Triggers Cancer Cell Suicide in Colorectal Cancer
Discover how AF8c, a novel multi-kinase inhibitor, induces apoptosis in colorectal cancer cells through ROS-mediated activation of DR5/Nrf2 pathways.
Arctigenin: Nature's Powerful Ally Against Breast Cancer
Explore how arctigenin, a natural compound from burdock plant, fights breast cancer through multiple molecular pathways including STAT3 signaling and SRC kinase inhibition.
Tiny RNA Guardians: How miR-15b/16 Protect Vision in Diabetes
Discover how miR-15b and miR-16 microRNAs protect retinal cells from hyperglycemia-induced damage in diabetes, offering new hope for preventing diabetic retinopathy.
The Double-Edged Sword: How a Cancer Drug Triggers Brain Cell Death
Explore how cytosine arabinoside (ara-C) activates neuronal death pathways while fighting cancer, revealing fascinating cellular suicide mechanisms.