Research Articles
The Invisible Hand: How IFN-γ Orchestrates the Immune Attack in Lichen Planus
Explore how interferon-gamma (IFN-γ) acts as the master conductor in lichen planus pathogenesis, driving immune-mediated destruction and offering new therapeutic targets.
Cancer Treatment Breakthrough: How p53 Protein Becomes a Secret Weapon in Anti-Cancer Drugs
Discover how p53 protein activation by Imiquimod and Compound C is revolutionizing cancer treatment through targeted apoptosis induction.
Trapping Cancer's Master Exporter: Novel CRM1 Inhibitors in MCL Treatment
How Selective Inhibitors of Nuclear Export (SINE) are revolutionizing Mantle Cell Lymphoma treatment by targeting CRM1/XPO1 protein.
The One-Gene Shortfall: How a Tiny Molecular Imbalance Sparks Pancreatic Tumors
Discover how MEN1 gene haploinsufficiency triggers pancreatic tumors, challenging the traditional two-hit theory of cancer development.
Copper Bullets to Cancer's Powerhouse: How a Smart Bomb Triggers Tumor Self-Destruction
Discover how CTB, a copper complex with TPP targeting, induces p53-dependent apoptosis in liver cancer through ROS-mediated Drp1 activation.
The Alkaloid Assassin: How a Plant Compound Hijacks Cancer Cell Machinery to Fight Brain Tumors
Discover how cyclovirobuxine D (CVB-D) from traditional Chinese medicine fights glioblastoma by exploiting cofilin and mitochondrial pathways.
The Mirror Molecules: How Left-Handed and Right-Handed Chemistry Could Revolutionize Cancer Therapy
Exploring the chiral properties of 3,4-dihydroquinazoline and its implications for cancer therapy development.
The Invisible Handshake: How mitoNEET and NAF-1 Team Up to Guard Our Cells
Discover how mitoNEET and NAF-1 proteins form a dynamic iron-sulfur cluster relay system to protect cells from oxidative stress and regulate mitochondrial health.
The Double Key: Unlocking Prostate Cancer's Resistance by Blocking Androgen and Estrogen Receptors
Exploring how simultaneous blockade of androgen and estrogen receptors could revolutionize prostate cancer therapy.
Molecular Sabotage: How a Traditional Abortion Drug Targets Leukemia Cells
Discover how trichosanthin from Traditional Chinese Medicine selectively targets leukemia cells through programmed cell death pathways.