Discover how ESR1 mutations in breast cancer create resistance to chemotherapy through the JNK/c-Jun/MDR1 pathway and the promising new treatment strategies emerging from this research.
Discover how Chitosan-Dextran sulfate coated doxorubicin loaded PLGA-PVA nanoparticles trigger apoptosis in resistant breast cancer cells through DNA damage.
Discover how vitamin D is emerging as an unexpected ally in breast cancer treatment, with genetic factors influencing its effectiveness and clinical trials showing promising results.
Discover how long non-coding RNA ZEB2-AS1 acts as a molecular mastermind in colon cancer development and progression.
Discover how N6-methyladenosine (m6A) RNA modifications and YTHDF2 protein drive endometrioid endometrial carcinoma progression through FENDRR degradation.
Explore how staphylococcal enterotoxin B (SEB) causes lethal toxic shock in mice through intranasal administration and its implications for human health.
Discover how miR-9 is revolutionizing meningioma prognosis as a novel biomarker for predicting malignant transformation in brain tumors.
Discover how the FoxO1 gene regulates stem cell behavior through mitochondrial dynamics and autophagy to build new bone tissue.
Discover how carnosol, a compound from rosemary, fights hepatocellular carcinoma through AMPK pathway activation and metabolic reprogramming.
Explore the cancer-fighting potential of indole-3-carbinol (I3C) and 3,3′-diindolylmethane (DIM) from cruciferous vegetables and their mechanisms of action.