Research Articles
The Cellular Tug-of-War: How Two Genes Dictate the Fate of Breast Cancer Cells
Explore the intricate relationship between cyclin D1 and Rb gene expression with apoptosis in invasive breast cancer. Discover how this molecular battle shapes cancer progression and treatment.
Starving Cancer: How Cutting Off Sugar Makes Tumors More Vulnerable to Destruction
Discover how inhibiting glycolysis sensitizes cancer cells to death receptor-induced apoptosis through AMPK activation and Mcl-1 translational blockade.
BR101801: A Triple-Target Therapy Revolutionizing the Fight Against Advanced Blood Cancers
Explore BR101801, a novel triple-inhibitor therapy targeting PI3Kγ, PI3Kδ, and DNA-PK for advanced hematologic malignancies. Learn about preclinical insights and clinical trial results.
[10]-Gingerol: How a Kitchen Staple Fights Aggressive Breast Cancer
Discover how [10]-gingerol from ginger fights triple-negative breast cancer through apoptosis induction and synergy with chemotherapy.
Unlocking the Kidney's Repair Shop: How a Protein Called ALK3 Reverses Fibrosis
Discover how the ALK3 protein receptor reverses kidney fibrosis and opens new frontiers in regenerative medicine for chronic kidney disease.
The Silent Kill Switch: How Your Immune System Orders a Clean Execution
Explore how apoptosis enables antibody-dependent cellular cytotoxicity (ADCC) - the immune system's clean execution mechanism for eliminating infected and cancerous cells.
HYS-072: A Novel Chrysin Derivative Fights Triple-Negative Breast Cancer
Discover how HYS-072, a novel chrysin derivative, effectively combats triple-negative breast cancer through apoptosis and autophagy induction.
Breaking the Shield: How a Novel Small Molecule AP030 Fights Leukemia by Targeting GCN2
Discover how the novel small molecule AP030 targets GCN2 to combat acute leukemia by disrupting cancer cell survival mechanisms in nutrient-starved environments.
The Hidden World Within: Unveiling Uterine Changes After Menopause
Explore the uterine changes and pathological processes that occur in postmenopausal women, including endometrial polyps, hyperplasia, and cancer detection methods.
The Body's Betrayal: How Our Arteries Turn to Bone and the Cellular Heroes Fighting Back
Discover how vascular calcification transforms flexible arteries into brittle bone-like structures through the Calcium-OPG-IGF1R signaling pathway.