Research Articles
Apoptosis-Related Genes (ARGs): A Comprehensive Guide to Functions, Analysis, and Therapeutic Targets
This article provides a comprehensive resource for researchers, scientists, and drug development professionals on Apoptosis-Related Genes (ARGs). It covers the foundational biology of key ARG families—including caspases, the Bcl-2 family, and p53—and their roles in intrinsic and extrinsic apoptotic pathways. The content extends to modern methodologies for ARG identification and analysis, common challenges in research, and the critical validation of ARGs as therapeutic targets in diseases like cancer. By synthesizing established knowledge with current research and clinical applications, this guide aims to bridge the gap between basic science and the development of novel apoptosis-targeting therapies.
Unlocking a Cellular Brake: How a Tiny Molecule Could Halt Stomach Cancer
Discover how microRNA miR-1287-5p suppresses gastric cancer by targeting LAMTOR3 protein, potentially leading to new cancer therapies.
The Blue Hope: How a Marine Algae Pigment Could Revolutionize Cancer Treatment
Discover how marennine, a blue-green pigment from marine diatoms, shows promising anti-cancer effects by inhibiting tumor cell proliferation and angiogenesis.
How an Asthma Drug Could Revolutionize Kidney Cancer Treatment
The unexpected anti-cancer potential of zafirlukast, a common asthma medication, reveals a new vulnerability in clear cell renal cell carcinoma (ccRCC).
A New Hope for Head and Neck Cancer: Targeting DNA Repair with Precision
Exploring the innovative clinical approach combining ACR-368 with low-dose gemcitabine for treating head and neck squamous cell carcinoma through precision oncology.
The Dental Detective Story: How a Common Bonding Agent Surprises Scientists by Protecting Your Teeth' Living Core
Discover how 10-MDP, a common dental adhesive, shows surprising pulp protection properties by influencing dental pulp stem cell behavior.
Nature's Arsenal: How Plant Compounds Are Revolutionizing Breast Cancer Care
Explore how natural compounds from soy, green tea, and flaxseed combat breast cancer through sophisticated molecular mechanisms and clinical evidence.
The Hidden Conductor: How a Novel Gene Directs Salmonella's Infection Orchestra
Discover how the trmE gene orchestrates Salmonella flagellar synthesis and virulence in this engaging scientific exploration.
The Cellular Detective: How Scientists Spy on Living Cells to Test New Medical Materials
Explore how Flow Cytometry and Fluorescence Microscopy work together to assess cell viability when testing bioactive glass and other medical materials.
Sunshine Vitamin vs. Breast Cancer: Unpack the Evidence
Exploring the epidemiological evidence linking vitamin D to breast cancer prevention through observational studies and clinical trials.