Research Articles
The Cell's Jekyll and Hyde: How a Single Protein Can Stop Cancer in Its Tracks
Discover how the WT1 protein acts as both growth promoter and tumor suppressor, activating anti-proliferative and apoptotic pathways to combat cancer.
PPAR-γ Agonists: A New Frontier in Ovarian Cancer Treatment
Exploring how PPAR-γ agonists cause growth arrest and apoptosis in human ovarian carcinoma cell lines - a breakthrough in cancer research
The Tiny Assassin: How a Microscopic Molecule Commands Cancer Cells to Die
Discover how miR-34c, a tiny RNA molecule, induces apoptosis in cancer cells by targeting the BCL2 protein, offering new hope for cancer treatment.
A Trojan Horse for Cancer Cells: Making Radiation Therapy Smarter
Discover how SM-164, a Smac-mimetic compound, acts as a Trojan horse to make breast cancer cells more sensitive to radiation therapy by triggering apoptosis.
The Cellular Rescue Squad: Unlocking How Brain Cells Cheat Death
Discover how JAK2 and STAT3 proteins form a cellular rescue team that fights to protect brain cells from glutamate-induced damage and apoptosis.
Breaking Bad: How an Arthritis Drug Could Help Fight a Rare Nerve Cancer
Discover how COX-2 inhibitors like etodolac trigger apoptosis in Malignant Peripheral Nerve Sheath Tumors by activating caspase pathways.
AF8c: How a Multi-Kinase Weapon Triggers Cancer Cell Suicide in Colorectal Cancer
Discover how AF8c, a novel multi-kinase inhibitor, induces apoptosis in colorectal cancer cells through ROS-mediated activation of DR5/Nrf2 pathways.
The Double-Edged Sword: How a Cancer Drug Triggers Brain Cell Death
Explore how cytosine arabinoside (ara-C) activates neuronal death pathways while fighting cancer, revealing fascinating cellular suicide mechanisms.
The Brain's Silent Alarm: Unraveling Schizophrenia's Apoptotic Mystery
Exploring the role of apoptotic proteins in schizophrenia and the discovery of elevated Bax/Bcl-2 ratio without caspase-3 activation in the temporal cortex.
How a Common Mold Fights Our Defenses to Make Us Sick
Discover how Aspergillus fumigatus, a common mold, actively suppresses human cellular defenses by inhibiting TNF-α induced apoptosis to cause serious infections.