Research Articles
The Cell's Tug-of-War: How a Weakness in a Rare Childhood Brain Tumor Was Uncovered
Scientists discover that a cancer's greatest strength—rampant protein production—can be its fatal flaw in Atypical Teratoid/Rhabdoid Tumors.
How a Beer Compound Could Revolutionize Cancer Treatment
Discover how isoxanthohumol, a compound found in hops, may overcome chemotherapy drug resistance in cancer treatment through groundbreaking research.
A One-Two Punch for Cancer: Turning a Tumor's Defense into its Downfall
Discover how MLN4924 and TRAIL combine to overcome cancer resistance through JNK-dependent c-FLIP downregulation in head and neck cancer cells.
Beyond the Usual Pathways: How Unconventional Secretion Fuels Cancer
Exploring how unconventional protein secretion in cancer cells reveals new biomarkers for early detection and treatment.
A Double Punch to Cancer: Turning Off a Cellular "Survival Switch" to Boost Therapy
Explore how researchers are enhancing cancer therapy by targeting the c-FLIPL protein to make cancer cells more susceptible to programmed cell death.
The Cellular Hypoxia Detective: How a Tiny Protein Fuels Cancer's Survival
Discover how the adaptor protein Ruk/CIN85 activates PAI-1 expression via HIF-1α in hypoxic tumors, revealing new cancer treatment possibilities.
Stopping Cancer in Its Tracks: How a Novel Compound Fights Colon Cancer Spread
Discover how the Alphavbeta3 integrin antagonist S247 decreases colon cancer metastasis and angiogenesis while improving survival in mice.
The Cell's Delayed Death Sentence: How a Cancer Drug Strikes with Perfect Timing
Discover how Interferon-alpha triggers cancer cell apoptosis through a sophisticated delayed timing mechanism during the cell cycle.
A Cellular Tug-of-War: How a New Drug Could Outsmart a Tenacious Blood Cancer
Discover how Aurkin-A, a novel TPX2-Aurora A inhibitor, disrupts alisertib-induced polyploidy in high-grade diffuse large B-cell lymphoma, offering new hope for cancer treatment.
Starving Cancer: How Cutting Off Sugar Makes Tumors More Vulnerable to Destruction
Discover how inhibiting glycolysis sensitizes cancer cells to death receptor-induced apoptosis through AMPK activation and Mcl-1 translational blockade.