Research Articles
How a Genetic Accident Creates Cellular Immortality: The Story of BCR-ABL and Apoptosis Inhibition in Leukemia
Explore how the BCR-ABL fusion protein inhibits apoptosis in chronic myeloid leukemia, creating cellular immortality and driving cancer progression.
Nature's Double Agent: How a Unique Fungal Fusion Fights Colon Cancer
Discover how Khz, a unique fusion of Ganoderma lucidum and Polyporus umbellatus, induces apoptosis in colon cancer cells through ROS generation and calcium signaling.
GnRH-II Antagonists: A New Frontier in Fighting Gynecological Cancers
Explore how GnRH-II antagonists trigger apoptosis in gynecological cancer cells through targeted molecular mechanisms, offering promising new treatment options.
The Double-Edged Sword of the Tiny: How Nano-Sized Copper Can Trigger Cellular Suicide
Exploring how nano copper induces apoptosis in PK-15 cells through mitochondria-mediated pathways and its implications for science and medicine.
Cellular Recycling Gone Rogue: How a Survival Mechanism Triggers Cell Death in Fruit Flies
Discover how autophagy, a cellular recycling process, paradoxically triggers cell death by degrading inhibitor of apoptosis dBruce in Drosophila oogenesis.
The Silent Saboteur: How Cellular Suicide Programs Hamper Immune Recovery in HIV Patients
Discover how the extrinsic apoptosis pathway undermines immune reconstitution in male ART-treated PLHIV, leaving them as immunological non-responders despite viral suppression.
The Hidden Casualties: How Hydrocortisone Reshapes Your Immune Army
Discover how hydrocortisone triggers apoptosis in dendritic cells and reshapes immune responses through cutting-edge research findings.
Frozen in Time: The Cellular Battle for Survival in a Revolutionary Cancer Therapy
Explore how cryopreservation affects mononuclear cell apoptosis in Extracorporeal Photopheresis (ECP) cancer therapy and the scientific breakthroughs in cellular preservation.
The Red Wine Molecule's Hidden Power: Turning the Tide Against Breast Cancer
Discover how resveratrol, a compound in red wine, induces apoptosis in aggressive breast cancer cells through PI3K/Akt and p53 signaling pathways.
A Cellular Saboteur: How a New Drug Tricks Cancer Cells into Self-Destructing
Discover how DPQZ, a novel antitubulin agent, induces apoptosis in oral cancer cells through Ras/Raf inhibition and MAPK activation.