Research Articles
The Epigenetic Casualty: How Diabetes Destroys a Key Gene Regulator in Insulin-Producing Cells
Discover how diabetes triggers proteasomal degradation of p300, a crucial epigenetic regulator in pancreatic beta-cells, leading to impaired insulin production and cell death.
The Silent Depletion: How Diabetes Steals Your Body's Natural Repair Cells
Explore how type 2 diabetes progressively depletes circulating progenitor cells, the body's natural repair system for blood vessels, and the scientific discoveries behind this process.
The Sweet Poison: How Excess Sugar Silences a Key Cell Survival Signal
Discover how high blood sugar epigenetically reprograms endothelial cells to self-destruct, leading to diabetic complications.
The Silent Alarm: A Cellular "Smoke Signal" Warns of Pre-Diabetes
Discover how the M30 antigen, a fragment from dying liver cells, serves as an early warning signal for pre-diabetes and impaired glucose tolerance.
The db/db Mouse: Decoding the Hidden Side of Diabetic Blindness
Discover how the db/db mouse model is revolutionizing our understanding of diabetic retinal neurodegeneration and leading to new treatments for diabetic blindness.
The Cell's Suicide Switch: How a Tiny Protein Could Revolutionize Diabetes Treatment
Discover how suppressing the PTEN protein protects insulin-resistant cells from apoptosis, offering new hope for diabetes treatment.
Unlocking the Secret to Protecting Kidney Cells in Diabetes: The Calcium Connection
Discover how store-operated calcium entry inhibition protects podocytes in diabetic kidney disease through groundbreaking research on calcium signaling and mitochondrial function.