Research Articles
Achilles' Heel: Starving the "Jekyll and Hyde" of Leukemia by Cutting Off its Fuel
Discover how scientists are targeting the metabolic vulnerability in Acute Myeloid Leukemia by exploiting its lactate dependency through SDH complex inhibition.
Unmasking the Double Agent: How a Common Protein Helps Leukemia Hide from Our Immune System
Discover how MUC1-C protein helps Acute Myeloid Leukemia evade immune detection by regulating PD-L1 expression through miRNA manipulation.
A One-Two Punch: New Combo Therapy Delivers a Knockout Blow to a Vicious Leukemia
Discover how combining FLT-3 inhibitors with HSP90 blockers creates a synergistic therapy that effectively targets acute myelogenous leukemia with mutant FLT-3.
The Unlikely Ally: How Bone-Building Cells Shield Leukemia from Treatment
Discover how osteoblasts protect acute myeloid leukemia cells from chemotherapy through the TNAP protein mechanism.
The Cellular Guardians and Their Doppelgänger: A New Clue in the Fight Against Leukemia
Exploring the complex interplay between p53 and p73 proteins in Acute Myeloid Leukemia and how it influences patient prognosis and treatment outcomes.
The Immortal Problem: How Scientists Learned to Keep Leukemia Cells Alive
Discover how scientists unlocked the secrets of the body's microenvironment to finally study B-cell chronic lymphocytic leukemia in the lab.
How a Simple Nutrient Cocktail Is Revolutionizing Leukemia Research
Discover how a specific nutrient mixture shows promising results in inhibiting the growth of acute promyelocytic leukemia HL-60 cells in laboratory and animal studies.
A One-Two Punch for a Formidable Foe: New Hope in AML Treatment
Discover how the synergistic combination of Apatinib and Homoharringtonine delivers a powerful blow to Acute Myeloid Leukemia cells through targeted mechanisms.
Rewriting the Rules of Blood Cancer Treatment: A New Hope After Transplant
Breakthrough research on Eprenetapopt with Azacitidine as maintenance therapy for TP53-mutated AML or MDS after stem cell transplantation
How Leukemia Hijacks the Bone Marrow: The Notch Signaling Story and Dexamethasone's Surprising Role
Discover how acute myeloid leukemia hijacks bone marrow through Notch signaling and how dexamethasone can target this mechanism to combat cancer growth.