Research Articles
The Hidden Switch: How a Tiny Genetic Change Influences Cleft Lip and Palate
Discover how rs2262251 in lncRNA RP11-462G12.2 influences non-syndromic cleft lip and palate through a complex genetic regulatory mechanism.
How Targeting a Cellular Fuel Source Could Revolutionize Blood Cancer Treatment
Discover how targeting NAMPT and NAD+ metabolism offers a promising new approach to treating adult T-cell leukemia/lymphoma and other aggressive blood cancers.
A Gut Feeling Against Cancer: How a Common Molecule Fights Breast Cancer
Discover how sodium butyrate, a gut-produced molecule, triggers apoptosis in breast cancer cells through ROS formation and mitochondrial impairment.
How a Dynamic Duo from Your Diet Could Fight Esophageal Cancer
Exploring the synergistic effects of β-carotene and vitamin D3 in fighting esophageal cancer through laboratory research
The Sugar-Clogged Highway: How High Glucose Disrupts Blood Vessel Repair
Discover how high glucose up-regulates microRNA-503, inhibiting IGF-1R and disrupting blood vessel repair in diabetes.
The Double-Edged Sword: How PPARβ/δ Ligands Cut Both Ways in Cancer Growth
Exploring the complex relationship between PPARβ/δ ligands and cancer growth, from contradictory findings to therapeutic potential.
The Cell's Suicide Pact: How a Natural Molecule Blocks a Deadly Signal
Discover how rottlerin prevents TNF-induced necrotic cell death by targeting Nox1 NADPH oxidase in this engaging scientific exploration.
The Rat Vascular Injury Model: A Tiny Surgeon's Guide to Healing Human Hearts
Explore how rat vascular injury models advance cardiovascular research through various surgical techniques and their clinical applications.
The Cellular Sabotage: How a Bacterial Invader Hijacks Our Immune System's Machinery
Discover how Brucella melitensis manipulates the SUMO-1 protein system to survive inside macrophages, revealing new insights into intracellular pathogen strategies.
The Estrogen Dilemma: Unraveling a Molecular Switch in Endometrial Cancer
Discover how estrogen leverages the AT1 receptor to drive endometrial cancer cell growth and the potential therapeutic implications.