Research Articles
Acridine Orange and DAPI Staining: A Robust Apoptosis Assay for Preclinical and Phase IIb Drug Development
This article provides a comprehensive resource for researchers and drug development professionals on the application of Acridine Orange (AO) and DAPI staining for apoptosis detection in preclinical and Phase IIb...
H&E Staining for Apoptosis Detection: A Comprehensive Protocol and Research Guide
This article provides a comprehensive guide for researchers and drug development professionals on utilizing Hematoxylin and Eosin (H&E) staining for apoptosis detection.
Uranyl Acetate-Lead Citrate Staining in EM: A Guide for Apoptosis Analysis and Safer Alternatives
This article provides a comprehensive resource for researchers utilizing uranyl acetate and lead citrate staining in transmission electron microscopy (ns/psTEM) for the analysis of apoptosis and cellular ultrastructure.
Apoptosis Morphology Across Cell Types: A Comparative Guide for Biomedical Research
This article provides a comprehensive comparative analysis of apoptotic morphological features across diverse cell types, essential for researchers and drug development professionals.
Nuclear Fragmentation in Apoptosis: A Stage-by-Stage Timeline from Initiation to Execution
This article provides a comprehensive analysis of the nuclear fragmentation timeline during apoptosis, a hallmark of programmed cell death.
Phase I Apoptosis: Decoding Cell Shrinkage and Eosinophilia as Key Early Biomarkers
This article provides a comprehensive analysis of the early phase (Phase I) of apoptosis, focusing on the critical morphological hallmarks of cell shrinkage and increased eosinophilia.
A Practical Guide to Distinguishing Apoptosis Phases by Light Microscopy
This article provides a comprehensive guide for researchers and drug development professionals on identifying the distinct phases of apoptosis using light microscopy.
Cytoskeletal Disassembly in Apoptosis: Mechanisms, Regulation, and Therapeutic Targeting of Apoptotic Body Formation
This article comprehensively examines the critical and regulated role of cytoskeletal degradation in the formation of apoptotic bodies (ApoBDs).
Decoding Apoptotic Morphology: A Comprehensive Guide to Phase IIa and IIb Distinctions for Research and Drug Development
This article provides a detailed analysis of the morphological and biochemical distinctions between the middle (IIa) and late (IIb) phases of apoptosis, critical stages where the cell commits to and...
Transmission Electron Microscopy for Early Apoptosis Identification: A Comprehensive Guide for Biomedical Research
This article provides a detailed guide for researchers and drug development professionals on utilizing Transmission Electron Microscopy (TEM) for the precise identification of early apoptotic cells.